Liver Function (P)
No description yet. This curated deck is ready for daily study.
Card preview (24)
What are the characteristics of the liver?
1) It is the largest organ 2) It is functionally complex 3) It is unique because it is resilient whereas it has the ability to regenerate cells destroyed by short-term injury or disease
The liver plays a critical role in what?
1) Metabolism 2) Synthesis 3) Detoxification 4) Elimination of substances from body
What are lobules?
These are the microscopic units that divide the liver
What is the function of lobules?
These are responsible for all metabolic and excretory functions
What is the characteristic of lobules?
These are 6- sided structures w/ centrally located vein and portal triads
What are the components of portal triad?
1) Hepatic artery 2) Portal vein 3) Bile duct
What are the 2 major cell types in the liver?
1) Hepatocytes 2) Kupffer cells
What are hepatocytes?
These are large cells radiating outward from central vein
What are kupffer cells?
These are macrophages lining the sinusoids
What are the functions of kupffer cells?
1) These act as phagocytes 2) These engulf bacteria, debris, and toxins
What are the biochemical functions done by the liver?
1) Excretory and Secretory 2) Metabolism 3) Detoxification and Drug Metabolism
In terms of excretory and secretory functions, what is the liver capable of?
1) Liver is the only organ w/ the capacity to rid body of heme waste 2) It secretes bile 3) It excretes bili
The bile is made up of what?
1) Bile acids or salts 2) Bile pigments 3) Chole
What is the volume of bile being produced by the body per day?
3 L
What is the volume of bile being excreted by the body?
1 L
What is bili?
It is the principal pigment in bile
Bili is derived from what?
From the breakdown of RBCs
What is the volume of bili produced by the liver per day?
200 - 300 mg/day
Most of the bili is eliminated where?
In feces
Some of the bili is eliminated where?
In urine
In terms of metabolism function, what can be synthesized by the liver?
1) Carbs synthesis 2) Lipid synthesis 3) Protein synthesis
What is the principle of carbs synthesis done by the liver?
The liver maintains stable glucose concentrated by storing it as glycogen and degrading glycogen when needed by the body
What is the principle of lipid synthesis done by the liver?
The liver breaks down fatty acids to form TAGs, phospholipids, or chole
In terms of detoxification and drug metabolism functions, what is the principle being done by the liver?
The liver prevents toxic or harmful substances from reaching systemic circulation by binding or chemical modification