Exam 2
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Chromosome
DNA and histone proteins - cell’s genetic material
DNA
self replicating material that’s the main component of chromosomes, carrier of genetic information
Nucleotide/Base Pair
A, T, C, G - pair together across the strands
Chromatin
makes up chromosomes - DNA and histone proteins
Genes
a distinct sequence of nucleotides on a section of a chromosome
Autosomes
chromosomes that aren’t sex chromosomes
Sex chromosomes
X and Y - determine sex
mRNA
transcribed from DNA, translated into proteins
protein
long folded chain of amino acid
amino acid
monomeric unit of a protein - differentiated by different R groups
Human genome is packaged into ____ chromosomes
46 - diploid,
haploid human genome contains approximately ____ genes
haploid human genome contains approximately ____ base pairs
3 billion
do you have 23 chromosomes or 46 (or 92)? Explain this question and its answer
23 pairs of chromosomes - one set from mom, one set from dad
how are nucleotides linked together – within a strand?
phosphodiester bonds
what holds base pairs together (A-T or C-G) – between strands?
Hydrogen bonds
Why does it require a higher temperature to “melt” CG bonds than AT bonds? Does heating DNA to these same temperatures break bonds between nucleotides within a single strand?
CG bonds are stronger - 3 H bonds vs 2
transcription vs translation
transcription - DNA being copied into mRNA translation - mRNA used as instructions for protein formation
DNA polymerase
enzymes that create DNA molecules by assembling nucleotides
RNA polymerase
enzyme that assembles RNA by copying template strand of DNA
tRNA
brings amino acids to the ribosome for peptide elongation, anti-codon matches with mRNA codon
ribosomes
catalyzes protein synthesis
Who are some of the scientists who contributed to our current understanding of genetics?
Walter Flemming - stages of mitosis Hershey and Chase - DNA is genetic material Watson and Crick - helical structure
Walter Flemming
1882 - described “chromatin threads” and named the stages of mitosis