Epithelial Cells
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What is extracellular matrix (ECM)?
material deposited by cells which forms the “insoluble” part of the extracellular environment
What is ECM generally composed of?
Fibrillar proteins (collagens, elastin) embedded in a hydrated gel (proteoglycans or ground substance)
What are some examples of poorly and highly organised ECM?
Poorly organised - Loose connective tissue Highly organised - Tendon, bone, basal lamina
What are the 5 main cell types?
Connective Contractile Haematopoietic Neural Epithelial
Connective tissue examples
Chondrocytes (cartilage) Osteocytes (bone) Fibroblasts (many tissues)
Contractile tissue examples
Skeletal, Cardiac and Smooth muscles
Haematopoietic cell examples
blood cells tissue-resident immune cells bone marrow cells
Neural cell examples
Neurones and Glial cells
What is carcinoma?
Epithelial cell cancer
What is sarcoma?
Mesenchymal (connective and muscle) cancers
What is leukaemia?
Haematopoietic cancer (bone marrow cells)
What is lymphoma?
Haematopoietic cancer (lymphocytes)
What is neuroblastoma?
Neural cell cancer (neurones)
What is glioma?
Neural cell cancer (glial cells)
What is epithelial cell cancer called?
carcinoma
What are cancers of mesenchymal tissue called?
Sarcoma
What are the 2 types of haematopoietic cancers?
Leukaemia and Lymphoma
What are the 2 types of neural cancers?
Neuroblastoma and Glioma
Functions of Epithelial cells
transport, absorption, secretion, protection
How are epithelial cells classified?
According to their shape and layering
What type of epithelium is flattened, plate shaped?
Squamous
Name the epithelium (shape+layering)
Simple squamous
What type of epithelium is arranged in columns?
Columnar
Name the epithelium (shape+layering)
Simple columnar