Trace and Toxic Elements

Extreme copper deficiency is seen in what fatal condition? a. Menkes’ disease b. Klinefelter’s syndrome c. Meese disease d. Kayser-Fleischer rings

Suppose the controller on a GFAAS is defective and the furnace is running cold. What effect will this likely have on the number of photons absorbed in the measurements? a. It will decrease the number of photons absorbed. b. It will increase the number of photons absorbed. c. It will have little effect. d. It is not a relevant question because AAS relies on emission of light from electronically excited atoms.

. Why would a clinical chemist develop an arsenic method that combines liquid chromatography with ICP-MS? a. To separate and quantitate several different arsenic-containing species in the same sample b. To eliminate interference by sodium from the analysis c. To shorten the run time of the measurement d. To lower the coefficient of variation for total arsenic measurements

Select the answer that designates three techniques widely used for elemental analysis, identified according to the initials for the techniques. a. AAS, ICP-MS, AES b. NMR, ICP-MS, AES c. GC-MS, ICP-MS, AES d. HPLC-ICP-MS, AAS, FTIR

One of the calcium isotopes ( 40Ca) has an atomic weight of 40. At what positions in a mass spectrum would singly and doubly charged ions of this isotope of calcium appear? Assume that singly charged Ca is listed first. a. 40 and 20 b. 40 and 60 c. 40 and 80 d. 40 and 40

. What primary purposes does the torch serve in ICP-MS? a. Vaporization, atomization, and ionization b. Vaporization, atomization, and electronic excitation c. Nebulization, atomization, and photon absorption d. Droplet transport, vaporization, and ion detection

. Manganese toxicity resembles the following disease: a. Parkinson’s disease b. Wilson’s disease c. Alzheimer’s disease d. Menkes’ disease

Iron is physiologically active only in the ferrous form in a. Hemoglobin b. Cytochromes c. Ferritin d. Transferrin

A metal ion required for optimal enzyme activity is best termed a(an) a. Cofactor b. Accelerator c. Coenzyme d. Catalyst

Which trace metal is contained in glucose tolerance factor? a. Chromium b. Copper c. Selenium d. Zinc

What metal may be used as a treatment for Wilson’s disease? a. Zinc b. Copper c. Molybdenum d. Fluorine

The metal ion essential for the activity of xanthine oxidase and xanthine dehydrogenase is a. Molybdenum b. Iron c. Zinc d. Manganese