Module 2 Cyclin/CDK complex

Part 2: RB is ____ and E2F activates the transcription of the ____ which binds to ____

Part 1: The first cyclin ____ binds to the ____ and ____ which Phosphorylates _____ that holds the ____

Part 3: ____ fully phosphorylates RB, causing the entire separation of E2F

Part 4: Cyclin E + CDK2 phosphorylates the protein ___ which is supposed to inhibit ____ Simultaneously, the E2F removes the ____ which is a repressor Both promotes the production of ____ leading into the ___

Part 5: Cyclin A replaces ____ to bind to ____ to cause the S Phase to progress The process above causes the production of ___ to cease Cyclin A binds to ___ so M phase can progress

Part 6: Cyclin A phosphorylates ____ Eventually, late in the ___ Cyclin A is replaced by ____ signifying the end of mitosis

Part 7: Cyclin B binds to ____, which leads to what is called the ____