ch9
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What is a gene pool
Complete set of all alleles present in a population
Large gene pool
Greater number of alleles=more genetic diversity
Small gene pool
Less number of different alleles=less genetic diversity
What is a mutation
A mutation is a permanent change in the nucleotide sequence of a section of DNA - Change of arrangement - Change in the amount of DNA in a cell - Mutations are permanent changes
How do mutations occur?
• DNA copying mistakes (chemical) • Viral infections (biological) • Radiation (physical)
What are point mutations?
A change to one base in the nucleotide sequence of a section of DNA
Base substitutions include:
• Silent • Missense • Nonsense
Frameshift mutations include:
• Insertion • Deletion
Silent
A single substitution may have no effect DNA triplet codes for the same amino acid
Missense
A single substituion that changes the amino acid This could change the protein
Nonsense
A single substitution that ends the sequence early Codes for a STOP, making protein nonfunctional
What are block mutations and its causes
Large sections of DNA are altered as a result of spontaneous errors during meiosis
Deletion
Removal of a section of DNA
Duplication
Replicating a section, lengthening the sequence
Inversion
Reversal of a section of DNA (flipping)
Translocation
Switching two sections of DNA
Insertion
Taking one section and placing it into another
Polyploidy
Organism with two or more sets on chromosomes Lethal in humans, common in plants 3n, 4n, etc
Aneuploidy
Addition or loss of one chromosome 2n + 1 or 2n - 1
What are selection pressures
Conditions or factors that influence the allele frequencies in a population Eg. Predator, disease, competition
Natural selection
• Genetic variation exists in a population • Selection pressure or who has the selective advantage/disadvntage • How the selection pressure effects certain individuals • Favoured alleles are passed down as they are inherited.
Genetic drift
Sudden or random change in allele frequency within the population
Bottleneck
• Natural disaster or human destruction • Almost the whole population is killed off, leaving only a few individuals
Founder’s effect
• Small population colonises a new area • Becomes isolated