Globular proteins
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globular properties
Globular proteins are compact, roughly spherical (circular) in shape and soluble in water
Globular proteins form a …….shape when folding into their tertiary structure because:
spherical their non-polar hydrophobic R groups are orientated towards the centre of the protein away from the aqueous surroundings and their polar hydrophilic R groups orientate themselves on the outside of the protein
How does globular proteins orientation enable water solubility
This orientation enables globular proteins to be (generally) soluble in water as the water molecules can surround the polar hydrophilic R groups
The solubility of globular proteins in water means they play important physiological roles as they can be
can be easily transported around organisms and be involved in metabolic reactions
The folding of the protein due to the interactions between the R groups results in globular proteins having
specific shapes
The folding of the protein due to the interactions between the R groups results in globular proteins having specific shapes. This also enables globular proteins to play physiological roles, for example,
, enzymes can catalyse specific reactions and immunoglobulins can respond to specific antigens
Some globular proteins are conjugated proteins that contain a prosthetic group eg. haemoglobin which contains the prosthetic group called haem what does conjugated mean and prosthetic group
a protein that contains a non protein chemical group such as a conjugated group or co factor. Proteins made up of juts amino acids are called simple proteins a prosthetic means a non protein part of a protein molecule