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Endocrinology Part 4 - Gonadal Hormones

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Total cards: 24•Content version: v4•Public deck•Updated: 8/1/2026

Card preview (24)

#1
Front (Question)

ovarian hormone synthesis

Back (Answer)

Ovarian Steroidogenesis

#2
Front (Question)

testicular hormone synthesis

Back (Answer)

Testicular Steroidogenesis

#3
Front (Question)

enzyme that converts cholesterol to pregnenolone

Back (Answer)

cholesterol side-chain cleavage enzyme

#4
Front (Question)

enzyme that converts pregnenolone to progesterone

Back (Answer)

3-beta-hydroxysteroid dehydrogenase

#5
Front (Question)

enzyme that converts progesterone to 17-OH progesterone

Back (Answer)

17-a-hydroxylase

#6
Front (Question)

enzyme that converts pregnenolone to 17-OH-pregnenolone

Back (Answer)

17-a-hydroxylase

#7
Front (Question)

enzyme that converts 17-OH-pregnenolone to 17-OH-progesterone

Back (Answer)

3-beta-hydroxysteroid dehydrogenase

#8
Front (Question)

enzyme that converts DHEA to androstenedione

Back (Answer)

3-beta-hydroxysteroid dehydrogenase

#9
Front (Question)

enzyme that converts 17-OH-pregnenolone to DHEA

Back (Answer)

17,20-Lyase

#10
Front (Question)

enzyme that converts 17-OH-progesterone to androstenedione

Back (Answer)

17,20-Lyase

#11
Front (Question)

enzyme that converts DHEA-S to DHEA

Back (Answer)

sulfotransferase

#12
Front (Question)

enzyme that converts androstenedione to testosterone

Back (Answer)

17-beta-hydroxysteroid dehydrogenase

#13
Front (Question)

enzyme that converts testosterone to dihydrotestosterone

Back (Answer)

5-a-reductase

#14
Front (Question)

where does conversion of testosterone → estradiol and androstenedione → estrone takes place?

Back (Answer)

Ovaries Peripheral tissues (aside from testes & ovaries)

#15
Front (Question)

females have testosterone due to this presence

Back (Answer)

DHEA

#16
Front (Question)

events that occur in peripheral tissues during ovarian/testicular steroidogenesis

Back (Answer)

• testosterone → (reduced) → dihydrotestosterone • adrenal androgen (DHEA) → testosterone • estriol (type of estrogen) → (hydroxylated) →estradiol • testosterone → estradiol • androstenedione → estrone

#17
Front (Question)

More potent than testosterone

Back (Answer)

Dihydrotestosterone

#18
Front (Question)

Responsible for masculinization of external genitalia (male gonads)

Back (Answer)

Dihydrotestosterone

#19
Front (Question)

What occurs when ↑ dihydrotestosterone in female

Back (Answer)

masculinization of female external genitalia

#20
Front (Question)

percentage of protein bound sex hormones

Back (Answer)

98-99% cannot fuse to the vascular system → cannot interact with the target cells

#21
Front (Question)

percentage of free/unbound sex hormones

Back (Answer)

1-2% biologically active

#22
Front (Question)

TRANSPORT PROTEINS OF GONADAL HORMONES

Back (Answer)

Sex Hormone-Binding Globulin (SHBG) Corticosteroid-Binding Globulin (CBG) Albumin

#23
Front (Question)

Transports androgens and estrogens

Back (Answer)

Sex Hormone-Binding Globulin (SHBG)

#24
Front (Question)

Binds adrenal cortex hormones

Back (Answer)

Corticosteroid-Binding Globulin