Lesson 3,4 Telomeres, DNA organization
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What are telomeres
Zones of repetative non-coding sequences at the end of a chromosome.
Why do we have telomeres
-critical info lost during dna replication -final rna primer put down on lagging strand not replaced with dna nucleotides.
What role do telomeres play
• prevent loss of critical info • prevent chromosomes from fusing to other chromosomes • prevent damage from other enzymes • play role in determining how many times a cell can divide therefore play role in determining lifespan of an organism
How are histones involved in dna organization
Histones are positively charger pr- - dna wraps around cluster of 8 histones to greatly reduce volume of dna
nucelosome- what is it
The repeating unit within the chromatin- dna wrapped around 8 histones
What do nucleosomes do
Compact themselves further into bundles.
Why is DNA organization so important?
Volume- limited space in the cell Protection- Damage to the DNA Access of information- find specific genes your looking for