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KIDNEY FUNCTION TEST part 6

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Total cards: 24•Content version: v4•Public deck•Updated: 8/1/2026

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#1
Front (Question)

The deficiency of this enzyme leads to Lesch-Nyhan Syndrome.

Back (Answer)

Hypoxanthine guanine phosphoribosyl transferase (Muricase)

#2
Front (Question)

It is a x-linked genetic disorder

Back (Answer)

Lesch-Nyhan Syndrome.

#3
Front (Question)

This disease is a self-destructive behavior such as chewing of fingertips and lips and is associated with delayed motor developments and “Gout-like swelling joints”

Back (Answer)

Lesch-Nyhan Syndrome.

#4
Front (Question)

This enzyme prevents reutilization of purine bases in the nucleotide salvage pathway.

Back (Answer)

Abnormal phosphoribosyl pyrophosphate synthetase

#5
Front (Question)

This disease occurs when monosodium urate precipitates from supersaturated body fluids.

Back (Answer)

Gout

#6
Front (Question)

The characteristics of this disease has a urate crystals in joint fluids.

Back (Answer)

Gouty arthritis

#7
Front (Question)

This is the other term for urate crystals

Back (Answer)

Tophi

#8
Front (Question)

This occurs in renal parenchyma.

Back (Answer)

Gouty nephropathy

#9
Front (Question)

This refers to the atrophy of the liver

Back (Answer)

Hypourecemia

#10
Front (Question)

What is the reference interval of females for hypourecemia?

Back (Answer)

F: 2.6 - 6.0 mg/dL M: 3.5 - 7.2 mg/dL

#11
Front (Question)

What is the conversion factor for uric acid?

Back (Answer)

0.059

#12
Front (Question)

This substance is the product of amino acid deamination, is often used for liver function test and urea production.

Back (Answer)

Ammonia

#13
Front (Question)

What is the primary site of Ammonia production?

Back (Answer)

Small intestine

#14
Front (Question)

Where is ammonia derived from?

Back (Answer)

• Breakdown of AA • Hydrolysis of urea

#15
Front (Question)

Ammonia exists in ionized or unionized form. Therefore, if Ammonia is in lower pH, what would be the result?

Back (Answer)

There is a formation of ammoniun ions

#16
Front (Question)

Ammonia exists in ionized or unionized form. Therefore, if Ammonia is in higher pH, what would be the result?

Back (Answer)

There is a formation of unionized form of ammonia

#17
Front (Question)

What is level of Ammonia if there is a severe liver damage?

Back (Answer)

Increased ammonia levels

#18
Front (Question)

How many ug/dL if the plasma level is low?

Back (Answer)

15 - 45 ug/dL

#19
Front (Question)

This method is quantitated by titration or colorimetry wherein Ammonia is released from an alkaline solution and determined by back titration with acid because NH3 is trapped in an acid medium of the diffusion cell. Despite the process, it is still time consuming with poor accuracy and precision.

Back (Answer)

Conway and Cook diffusion method (Microdiffusion method)

#20
Front (Question)

If Conway and Cook is quantitated by titration. How about for Forman’s Resin absorption method?

Back (Answer)

Berthelot reaction/ Nesslerization

#21
Front (Question)

This method of determination of Ammonia uses cation-exchange resin. Wherein NH3 is absorbed by the resin and eluted.

Back (Answer)

Forman’s Resin Absorption Method

#22
Front (Question)

What is the normal value of Forman’s Resin Absorption Method?

Back (Answer)

16 - 33 umol/L

#23
Front (Question)

In Kunahashi, Ishihora and Euhera method, NH3 is obtained through the use of this column.

Back (Answer)

Dowax column

#24
Front (Question)

This method is assayed using the Berthelot method.

Back (Answer)

Kunahashi, Ishihora and Euhera method