immunology
暂无描述。系统推荐的高质量记忆内容，适合每天坚持背诵学习。
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innate involves
phagocytes neutrophils macrophages
adaptive involves
lymphocytes
macrophage engulfs bacterium into a
phagosome
the phagosome then fuses with another vesicle called the
lysosome
lysosomes are full of chemicals and enzymes that will
kill the bacterium
monocytes and macrophages are made in
bone marrow (stem cells)
macrophages are found in
tissues
macrophages give off chemicals that
restrict blood flow away from the site of injury
macrophages produce
cytokines
neutrophils are also involved in
phagocytosis
eosinophil
parasitic infections allergy and asthma
anaphylactic shock is caused by
mast cell degranulation
mast cells protect against
parasites
mast cells contain
histamine
basophil
store histamine
functions of complement
induce lysis of microbes MAC promote phagocytosis stimulate inflammation
cytokinase
chemicals used by cells to communicate with other cells
maturation of T cells and t cell precursors (macrophages, dendritic cells)
thymus
spleen: white pulp has 2 zones
b cell and t cell
spleen: red pulp
function is to filter blood
t cell are responsible for
cell mediated immunity and assisting B cells CD4 helper and CD8 killer
t helper cells
cannot kill infected cells or pathogens
cytotoxic t cells
when exposed to infeted cells they release perforin form PORES in target cells induce apoptosis
Th2 cells
produce different potent cytokines which are regulating mast cells and eosinophil activity