Specific immune respone
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Where are B-cell And T-cells formed
Bone marrow
Where do B-cells and T-cells mature
B-cells - bone marrow T -cells - Thymus
Naive B-cell
A B-cell that has never encountered an antigen before
First step of the primary immune response
The naive B-cell has complementary receptors to the pathogens antigen and so they bind
Second step of the primary immune response
The naive B-cell internalises and processes the pathogen and then displays it on the cell surface membrane as a processed antigen
Third step of the primary immune response
The processed antigen is complementary to receptors on the helper t-cell so they bind. After the naive b-cell and helper t-cell bind, the helper t-cell releases a chemical which causes the naive b-cell to clone by MITOSIS and differentiate
Forth step of the primary immune response
The naive b-cell differentiates into either a plasma cell or a memory b-cell
Role of the plasmsa cell
Secretes monoclonal antibodies These antibodies are complementary to the specific antigen on the pathogen. These antibodies attach to antigens on pathogens and destroy them
Role of memory b-cell
The memory cell circulates the blood, ready to divide if the same antigen / pathogen is encountered again
Secondary immune response
Much faster as memory b-cells will recognise the specific antigen on the pathogens surface so antibodies will be produced much faster and symptoms / ilness from the pathogen wont happen