Experimental Research Design (2)

observational method experimental method comparitive method

where we watch nature with no manipulation at all, observation only and any techniciancan do it

where we design the tests and manipulate the conditions (specific object, groups assesed individually, technicians are trying to control more parameters, experts required)

where we compare across systems or species

same hypothesis tested over 10 years in 6+ countries in many different places within those countries and many different scientists all come up with the smae conclusion, it then becomes a theory

a fundamental cell communication pathway that controls how cells grow, divide, move and specialize

quiescent neural progenitor

Amplifying Neural progenitor

bind to Dkk1 and prevent neurogenesis from happening

binds to dye

used to identify neuronal development stages

region where neurogenesis takes place

activated when apoptosis is going to occur

programmed cell death (aged, no more benefit to body/organ)

used to determine how much cell death is occuring, increase in cell population = increase in cell death

marker for imature neurons

increases neurogenesis, increased neural stem cell self renewal and number of progenitors, increase in immature neurons, increased branching in new neurons