molecular collagen structure
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Collagen is the most common structural protein found in vertebrates In vertebrates it is the component of connective tissue which forms:
Tendons Cartilage Ligaments Bones Teeth Skin Walls of blood vessels Cornea of the eye
Collagen is an
insoluble fibrous protein
Collagen is formed from
three polypeptide chains closely held together by hydrogen bonds to form a triple helix (known as tropocollagen)
Each collagen polypeptide chain is a .. what shape and what does it contain
is a helix shape (but not α-helix as the chain is not as tightly wound) and contains about 1000 amino acids with glycine, proline and hydroxyproline being the most common
In the primary structure of collagen almost
every third amino acid is glycine This is the smallest amino acid with a R group that contains a single hydrogen atom
Glycine tends to be found on the ……. of the polypeptide chains allowing the three chains to be
inside Glycine tends to be found on the inside of the polypeptide chains allowing the three chains to be arranged closely together forming a tight triple helix structure
Along with hydrogen bonds forming between the three chains there are also covalent bonds present where are they found
Covalent bonds also form cross-links between R groups of amino acids in interacting triple helices when they are arranged parallel to each other.
he cross-links hold the collagen molecules together to form
fibrils
The collagen molecules are positioned in the
fibrils so that there are staggered ends
When many fibrils are arranged together they form collagen
collagen fibres
Collagen fibres are positioned so that they are lined up with the forces they are
withstanding