Introduction to drosophila
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What are hox genes and what do they do?
They are zygotic genes They act along the A-P axis and gives each segment its unique character- wings, leg, antennae
What happens to future mesoderm in gastrulation?
It invaginates to form a furrow along the ventral midline
What happens to ectodermal cells in gastrulation?
They leave the surface individually and form a layer of prospective neural cells
What else does the ectoderm form in gastrulation?
Ectodermal cells are dragged in behind both the anterior and posterior midgut to form the foregut and hindgut
What is a germarium?
Where oocyte development begins It is a mass of stem cells
Where is bicoid and oska mRNA localised in the oocyte?
Bicoid- anterior end Oskar- posterior end
What transports bicoid on the mictrotubule and in which direction?
Towards negative end- by dynein
What transports oskar on the microtubule and in which direction?
Towards positive end- by kinesin
What are the steps in oogenesis?
• A stem cell in the germarium divides asymetrically- stem cell and a cytoblast • Cytoblast undergoes 4 mitotic divisions- 16 cells- cyst • One of these cells becomes a oocyte, the other 15- nurse cells • The somatic ovarian cells make up a sheath of follicle cells around the nurse cells and oocyte- egg chamber • The follicle cells have a key role in patterning the egg’s axes • Eventually the oocyte fills the whole egg chamber- mature egg is released from the ovary and laid