Innate Immunity - Tutorial 3
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Name the three lines of defence and classify each as either innate (non- specific) or adaptive (specific) defence
First line: innate/non-specific - defences which aim to prevent a wide variety of microorganisms from entering the body. Second line: innate/non-specific - defences which help eliminate a wide variety of microorganisms which have penetrated the body. Phagocytosis, inflammation, fever, antimicrobial substances. Third line: adaptive/specific - Helps to elongate specific microbes which have penetrated the body and protect the host against future attack by the same organism. They are called acquired/adaptive because they develop as a result of contact with the microbe.
State the overall functions of inflammation
• Destroy the microbe (& its end products). • Prevent the spread of the microbe (by building a wall of fibrin around it so it is confined to a local area). • Clear the site of cellular debris and dead microbes • Repair the damaged tissue.
Name and describe the three stages of inflammation
• Vasodilation and increases blood vessel permeability • Phagocyte migration to the damaged tissue and phagocytosis of bacteria and cellular debris 3.Tissue repair