TRYPSIN
暂无描述。系统推荐的高质量记忆内容,适合每天坚持背诵学习。
卡片预览 (16 张)
Where is trypsin solely produced?
Acinar cells
Cleaves peptide bonds formed between the -COOH group of lysine or arginine with other amino acids
Trypsin
trypsinogen- & trypsinogen-2
Zymogen
What is the activator of trypsin?
Enterokinase
Trypsin is inactivated by?
a-1 antitrypsin a-2- macroglobulin
What is the charge classification of trypsin 1 and 2?
TRYPSIN-1 (Cationic) TRYPSIN-2 (Anionic)
Where is trypsin 1 elevated?
Acute Pancreatitis Chronic Renal failure Cystic Fibrosis
Explain why trypsin 1 is elevated in acute pancreatitis.
TRY-1 rises in parallel with serum AMY activity
Serum trypsinogen-2 increases more than trypsinogen-1 (10-fold greater)
Acute pancreatitis
Larger amounts are excreted into urine.
Acute Pancreatitis
Trypsin assays are currently being used for differentiating the cause of _________________?
acute pancreatitis
more elevated in alcohol-associated pancreatitis
Trypsinogen-2 Trypsin-2-AAT
more elevated in biliary pancreatitis
Trypsinogen-1, AMS & LPS
What are the methods of determination of trypsin?
Commercial IMMUNOASSAYS Urinary trypsinogen-2 test strip
Commercial IMMUNOASSAYS detects?
o Trypsinogen-1 o TRY-1 o TRY-1-a1-antitrypsin complex
based on the use of immunochromatography with monoclonal antibodies.
Urinary trypsinogen-2 test strip