Claisen and Cross Claisen condensation

• Which of the following is a product formed in Claisen condensation? a) β- ester b) β-ketone c) β-keto ester d) Y-diketone

• Which type of precursor is used as reactant in intramolecular Claisen condensation? a) One molecule with an ester end b) Two molecules of ester c) One molecule with two ester ends d) One molecule of ester and enolate

• Which of the following stamen is incorrect about Claisen condensation? a) The product is a β-keto ester which resists deprotonation by the strong base in the reaction mixture b) The reaction involves the condensation of two esters in the presence of strong base c) A strong base is required to remove H+ from an α-H position in one of the starting esters d) A strong base is required to remove H+ from an α-H position in one of the starting esters

• Lye is used in soap-making. Lye is a concentrated solution of which ionic compound? a) K2CO3 b) CuSO4 c) NaOH d) NaCl

• Which of the following term describe saponification? a) Cleaving of ester molecules into carboxylic acid and alcohol b) Dehydration synthesis by removing water c) Hydrolysis of a salt by adding a weak acid d) Synthesis of two alkyl groups to make an ether

• Which of the following is considered a useful alkali in saponification reactions? a) CCl4 b) Cl– c) NaOH d) Pb+

• Saponification value is the number of milligrams of KOH required to saponify what present in the 1g of oil or fat? a) Salts b) Hydrocarbon c) Fatty acids d) unsaturation

• Which of the following is a product formed in Claisen condensation? a) β- ester b) β-ketone c) β-keto ester d) Y-diketone

• Which of the following compound is an industrial manufacturing product by saponification? a) Sodium chloride b) Potassium hydroxide c) Glycerol d) Sodium hydroxide

• Which of the following fat or oil is unsaponifiable? a) Paraffin wax b) Bee wax c) Olive oil d) Shea butter

• Which of the following statement is true about saponification value of oil? a) The shorter the chain of fatty acid, the higher is the saponification value b) The shorter the chain of fatty acid, the higher is the saponification value c) The higher the saturation in chain of fatty acid, the lower is the saponification value d) The lower the saturation in chain of fatty acid, the higher is the saponification value

• Soap can be precipitated out by salting by using which chemical compound? a) Sodium chloride b) Potassium hydroxide c) Glycerol d) Sodium hydroxide

• Which of the following stamen is incorrect about Claisen condensation? a) The product is a β-keto ester which resists deprotonation by the strong base in the reaction mixture b) The reaction involves the condensation of two esters in the presence of strong base c) A strong base is required to remove H+ from an α-H position in one of the starting esters d) A strong base is required to remove H+ from an α-H position in one of the starting esters

• Which type of precursor is used as reactant in intramolecular Claisen condensation? a) One molecule with an ester end b) Two molecules of ester c) One molecule with two ester ends d) One molecule of ester and enolate

• Dieckmann Condensation is intramolecular condensation of ……. to form cyclic product. a) diamide b) diol c) diester d) diketone

• What is the other name for the intramolecular Claisen condensation? a) Perkin condensation b) Stobbe condensation c) Knoevenagel condensation d) Dieckmann condensation

• Ethylamine can be prepared by the action of bromine and caustic potash on which compound? a) Acetamide b) Propionamide c) Formamide d) Methyl cyanide

• The amine formed from an amide by means of bromine and alkali has how many number of carbon atoms? a) Same number of C atoms as that of amide b) One less C atom than that of amide c) One more C atom than that of amide d) Two more C atoms than that of amide

• When methyl iodide is heated with ammonia, what is the product obtained? a) Methylamine b) Dimethylamine c) Trimethylamine d) A mixture of the above three amines

• Reduction of nitroalkanes yields which compound? a) Acid b) Alcohol c) Amine d) Diazo compounds

• Which one of the following compound gives a secondary amine on reduction? a) Nitromethane b) Nitrobenzene c) Methyl isocyanide d) Methyl cyanide

• The Hinsberg’s method is used for which of the following? a) Preparation of primary amines b) Preparation of secondary amines c) Preparation of tertiary amines d) Separation of amine mixtures

• What is the name of the reaction when acetamide changes into methylamine? a) Hofmann bromamide reaction b) Hofmann reaction c) Friedel-Craft’s reaction

• When ethanol is mixed with ammonia and passed over alumina the compound formed is which compound? a) C2H5NH2 b) C2H4 c) C2H5OC2H5 d) CH3OCH3