test 5

what does CAF stand for

what does TAM stand for

are tumors homogenous populations of cells

cancer is a disease of —

normal cells form the —, the supportive connective tissue of the tumor

stromal cells are — in origin (cell type)

many signalling processes seen in tumor progression also occur in — —-

what does EMT stand for

what does MET stand for

— promote epithelial cells to move/metastasize

—- recruits fibroblasts and macrophages which become CAFs and TAMs, form tumor stroma, and promote angiogenesis

PDGF recruits — and — (immune cells)

fibroblasts and macrophages recruited by carcinoma PDGF become — and —

fibroblasts and macrophages recruited by carcinoma PDGF form the tumor —-

fibroblasts and macrophages recruited by carcinoma PDGF promote — (but leaky capillaries)

true or false: an individual’s immune system is able to distinguish between the individual’s cells and foreign cells

true or false: an individual’s immune system is able to distinguish between the individual’s normal cells and the individual’s cancer cells

immune system cells can be “typed” by — markers

what does CD markers stand for

where are CD markers in the cell

which immunity? recognition of general molecular patterns or motifs in pathogens but absent from hosts, also damage or death associated molecules

which immunity? highly specific, capable of distinguishing between molecules or regions of molecules that differ only slightly

which immunity? many families with few members of highly conserved receptors

which immunity? extremely diverse repertoires of T cell and B cell antigen receptors