Genetics & Inheritance
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dominant gene
an allele that masks the effect of an another
recessive gene
an allele that is masked by the alternative (dominant)
gene
the factor that determines an inherited characteristic, located in chromosomes
allele
an alternative form of a gene
progeny
offspring
principle of segregation
the principle that the alleles for a trait are separated during the formation of gametes
monohybrid cross
a mating between individuals in which only one pair of contrasting alleles is being considered
homozygous
a.k.a. pure-breeding individual has same alleles for particular characteristic
heterozygous
a.k.a. hybrid individual has 2 different alleles for particular characteristic
phenotype
physical appearance of an individual determined by the expression of the alleles for that characteristic
genotype
the genetic make-up of an individual determined by the alleles for the characteristic being considered
first filial generation f1
offspring of the first set of parents
second filial generation f2
offspring from crossing the first filial generation
loci/locus
part of the chromosome where that gene is located
What did Gregor Mendel establish 2
• the various hereditary characteristics were controlled by factors (genes) that occurred in pairs • during the formation of the gametes, the pairs of each factors seperate and each gamete receives only one set of factors with the other set going to the other gamete not codominance or incomplete dominance!
Pedigree
a symbolic family tree showing males and females and those individuals that have a particular characteristic or disease
Autosomal
concerned with non-sex chromosomes
punnet square
predicts the probability of the genotype & phenotype of the offspring
codominance 2
two or more alleles are equally dominant both phenotypes are expressed e.g. I^A & I^a
multiple alleles
more than 2 alleles for a specific characteristic e.g. blood groups
genetic counselling
advice regarding the risks of genetic disorders in future children
Red-green colour blindness 2
• X-linked recessive • Lack the ability to discriminate between the colours green and red.
Haeomophilia 3
• X-linked recessive • The blood clots very slowly or not at all. • Prominent in the royal families that descended from Queen Victoria
Phenylketonuria 2
• Autosomal recessive • Can not produce the enzyme needed to break down phenylalanine which then accumulates, causing brain deformities and mental retardation.