Chapter 8
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Natural immunity
occurs without medical intervention
Artificial immunity
occurs with medical intervention
Active immunity
Body produces its own antibodies and memory cells
Passive immunity
Antibodies are obtained from an external source
Natural active immunity
no medical intervention, self-antibodies, lasts longer.
Examples of natural active immunity
recovering from chickenpox after being infected.
Natural passive immunity
No intervention, external antibodies, short-lived.
Examples of natural passive immunity
Antibodies from mother to child through milk or across the placenta.
Artificial active immunity
Medical intervention, self-antibodies, lasts longer.
Examples of artificial active immunity
Vaccines
Artificial passive immunity
Medical intervention, external antibodies, short-lived.
Examples of artificial passive immunity
Antibody injections or infusions such as antivenom for snake bites.
Vaccine
A medical treatment typically containing antigens that stimulate the adaptive immune response to safely create immunity to a pathogen.
How do vaccines work?
APCs present antigens of the inactivated or fragmented pathogen to T and B cells, binding to the ones with complementary receptors. These cells then undergo clonal selection and differentiation, becoming antibody-secreting plasma cells, cytotoxic T cells, and memory cells which stay in the body for a long time, and can respond faster to future infection.
Why do vaccines take time to become effective initially?
Because the immune system needs time to produce enough antibodies to grant immunity.
What components might a vaccine need to resemble a pathogen?
-weakened or dead pathogens. -Toxoids -specific proteins on the surface of pathogens -RNA
Toxoids
Toxins that have been altered so they can’t cause disease
Vaccination program
A series of vaccinations designed to create long-term immunity to a disease.
Booster vaccine/booster shot
A supplementary vaccine that replenishes and strengthens an individual’s immunity to a disease long after their initial vaccination.
Why are booster shots needed
Because the amount of antibodies depletes over time
Herd immunity
Protection against a disease given to non-immune people when most of the population is immune
Primary immune response
The reaction of the adaptive immune system to a new unfamiliar pathogen
Secondary immune response
The heightened reaction of the adaptive immune system upon re-exposure to a pathogen
Infectious disease
any disease caused by a pathogen