nervous tissue I
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cell body
• receptive area in multipolar neurons • most protein synth done here • membrane specialized for impulse generation
Nissel bodies
basophillic clump of rER in neurons
what does the nucleus of the cell body look like
euchromatic with a central nucleolus that’s spherical and dense
In general do neural cells divide? whats the exception?
• no, no mitosis - exception is neural stem cells- turn themselves into neurons when there is damage
what are the neurofilaments
intermediate filaments, microfilaments, microtubules
axon hillock
origin of the axon, funnel shaped with no rER- pale staining
chromatolysis
dissolution of nissel bodies (accum of rer)
dentrites
• radiate from soma • increase receptive area of neuron • antennas for info that they bring to cell body and then send down the axon • NEVER mylinated • no Golgi, may have RER, ribosomes, mitochondria
axon
• no rer • has mitochondria, ser, vesicles microtubules and neurofilaments • transmit impulse from cell body to other neurons or muscle cells
axolemma
axon cell membrane
axoplasm
axon cytoplasm
initial segment of the axon
• distal to cell body but proximal to where it is myelinated - action potential initiated here
collateral branches
branches near hillock
if there is injury to a neuron what regenerates and what degenerates
the proximal portion regenerates distal degenerates
terminal arborizations
end of axon where there is a split into branches
terminal buttons
little dilated ends of arborizations (lil feet) form synapses some local protein snyth occurs here
axoplasmic transport
• movement of macromolecules, organelles and vesicles from/to axon cell body • can be anterograde or retrograde
Antegrade axoplasmic transport
• requires KINESIN (microtubule) • slow transport- carries substances from the cell body to the terminal buttons; for actin molecules, neurofilament proteins and tubulin molecules • fast- requires ATP
Retrograde axoplasmic transport
• carries macromolecules, organelles and vesicles TO the cell body • requires DYNEIN (microtubule) • VIRUSES AND TOXINS THAT ENTER NERVE ENDINGS TRAVEL TO THE CNS VIA RETROGRADE TRANSPORT • FAST TX- bidirectional and requires ATP • carries ser, synaptic vesicles, mitochondria, sugars neurotransmitters and calcium
bipolar axon
• two processes - in special senses- smell vison hearing equilib
unipolar axon
single process arising from cell body which secondarily bifurcates into 2 processes t shaped impulses transported down axon bypassing the cell body in CN sensory ganglia and Dorsal root ganglia
multipolar axon
• most common kind • numerous dendrites and central process of axon • includes motor and interneurons
what are the functional classifications of neural fibers?
1)motor efferent -skeletal motor-somatic efferent- skeletal muscle fibers -visceral motor- visceral efferent-smooth muscle/cardiac 2) -sensory afferent - somatic= receive sensory from stimuli in environ visceral- from visera 3) interneurons- confined to CNS
neuroglia
• provide physical and physiological support for nerve cells • more numerous than nerve cells • can divide so can form tumors