Random MCQs - high yield
No description yet. This curated deck is ready for daily study.
Card preview (19)
Vasodilation mediators?
Prsotaglandins and NO and histamine
Vascular permeability mediators?
NO, histamine
Pain mediators?
Heat mediators?
Transmigration of neutrophils is facilitated by what protein?
PECAM-1 (aka CD31)
What do neutrophils use to attach to endothelial walls?
Integrins (neut) to integrin ligand (ICAM-1) on endothelial cells
What is the alternative (M2) activation pathway of macrophages?
They can be activated to induce wound repeat and healing. This is promoted by IL-4. The classic destructive classical pathway is inhibited by IL-13.
Which signalling pathway are most commonly implicated in angiogeneis?
VEGF and NOTCH signalling.
Men 1 is what?
Men 2A is what?
Men2B is what?
SCC in lung causes what paraneoplastic syndromes?
PTHrP and hypercalcaemia Pancoast syndrome
SCLC cauases what paraneoplastic?
Lambert eatan SIADHA
What is the gene affected in Marfan’s?
Fibrillin
What causes pigmentation of cells in the spleen in patients with malaria?
Hemozin - digested heme eaten by the the parasite
Are there fibroblasts in the brain?
No
If there are no fibroblasts in the brain, then what fills damaged tissue after say a stroke?
Glial cells. Difficult to distinguish from tumour.
What is sirtuin 1?
Its a protein that is released during intermittent fasting that is great. Reduces adipose tissue, makes you live longer.