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iPSCs

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Total cards: 4•Content version: v4•Public deck•Updated: 8/1/2026

Card preview (4)

#1
Front (Question)

How many T. factors in a ‘cocktail’ can induce pluripotency?

Back (Answer)

4

#2
Front (Question)

What are the advantages of iPSCs?

Back (Answer)

• No embryo needed • Can get individual specific cells- personalised • Vastly renewable • Easily accessible

#3
Front (Question)

What are the obstacles in the therapeutic application of iPSCs in humans?

Back (Answer)

• Use of viral vectors for gene delivery carries the risk of insertional mutagenesis- tumourigenicity • Low efficiency and SLOW kinetics of reprogramming cells • Lack of robust and reliable differentiation protocols for human iPS cells

#4
Front (Question)

What are the key 4 transcription factors?

Back (Answer)

Oct4 Sox2 cMyc Klf4