Muscles
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What are 4 functions of muscles?
• Movement • Maintain posture • Stabilise joints • Generate heat
What are the 3 muscle types/
• Skeletal • Cardiac • Smooth
What is hypertrophy?
Enlargement
What are 3 main histological features of skeletal muscle?
• Myofibres have cross striations • Myofibres are long, unbranched and multinucleated • Nuclei occur at periphery of fibre
What is the hierarchy of skeletal muscle in descending order?
• Muscle • Muscle fascicle • Muscle fibre • Myofibril • Myofilaments
Name 2 myofilaments
• Actin 2. Myosin
Name 3 types of CT of skeletal muscles
• Epimysium • Perimysium • Endomysium
What is epimysium?
Connective tissue which surrounds the outside of an entire muscle
What is perimysium?
Connective tissue which surrounds the outside of a muscle fascicle
What is endomysium?
Connective tissue which surrounds the outside of a muscle fibre
What is the I band?
Composed of actin myofilaments anchored to the Z-line
What is the A band?
Overlap of actin anchored to the Z-line and myosin anchored to the M-line
What is a sarcomere?
Distance between two Z-lines
What is the only band that remains the same length when a muscle contracts?
A band
What is the sarcolemma?
Plasma membrane of a muscle fibre
What are transverse tubules?
Tubular invaginations of the sarcolemma
What is the function of transverse tubules?
Carry a wave of depolarisation into the muscle fibre
What is the sarcoplasm?
Cytoplasm of muscle fibre
Name 4 structures found in the sarcoplasm
• Myofibrils • Mitochondria • Sarcoplasmic reticulum • Myoglobin
Where is cardiac muscle found?
The heart
Name 3 histological features of cardiac muscle
• Striated • Branched cells joined by intercalated discs • Nucleus positioned centrally in the fibre
What are intercalated discs?
Adhesion specialisations comprising fascia adherens and nexus
Where is smooth muscle found?
Tubular organs
Name 3 histological features of smooth muscle
• Non-striated • Spindle shaped cells • Corkscrew shaped nucleus