Unit 3
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decrease in the number of hormone receptors, typically in response to chronically excessive levels of a hormone
downregulation
(also, T3) amino acid-derived thyroid hormone that is less abundant but more potent than T4
triiodothyronine
bone tissue; a hard, dense connective tissue that forms the structural elements of the skeleton
osseous tissue
endocrine glands located at the top of each kidney that are important for the regulation of the stress response, blood pressure and blood volume, water homeostasis, and electrolyte levels
adrenal glands
hypothalamic hormone stored in the posterior pituitary gland and important in stimulating uterine contractions in labor, milk ejection during breastfeeding, and feelings of attachment (produced by males and females)
oxytocin
large endocrine gland responsible for the synthesis of thyroid hormones
thyroid gland
the human body’s three-stage response pattern to short- and long-term stress
general adaptation syndrome (GAS)
cylinder-shaped bone that is longer than it is wide; functions as a lever
long bone
tubular shaft that runs between the proximal and distal ends of a long bone
diaphysis
deepest region of the adrenal cortex, which produces the steroid sex hormones called androgens
zona reticularis
opening or depression in a bone
hole
second messenger that, in response to adenylyl cyclase activation, triggers a phosphorylation cascade
cyclic adenosine monophosphate (cAMP)
viscous fluid in the central cavity of thyroid follicles, containing the glycoprotein thyroglobulin
colloid
connective tissue in the interior cavity of a bone where fat is stored
yellow marrow
primary cell in mature bone; responsible for maintaining the matrix
osteocyte
cells, tissues, and organs that secrete hormones as a primary or secondary function and play an integral role in normal bodily processes
endocrine system
cytosolic enzyme that deactivates and degrades cAMP
phosphodiesterase (PDE)
condition characterized by abnormally high levels of calcium
hypercalcemia
region of the epiphyseal plate where chondrocytes from the proliferative zone grow and mature and contribute to the longitudinal growth of the epiphyseal
zone of maturation and hypertrophy
inner layer of the adrenal glands that plays an important role in the stress response by producing epinephrine and norepinephrine
adrenal medulla
cells, tissues, and organs that secrete substances directly to target tissues via glandular ducts
exocrine system
sheet of hyaline cartilage in the metaphysis of an immature bone; replaced by bone tissue as the organ grows in length
epiphyseal plate
steroid hormone secreted by the testes and important in the maturation of sperm cells, growth and development of the reproductive system, and the development of secondary sex characteristics
testosterone
intermediate region of the adrenal cortex that produce hormones called glucocorticoids
zona fasciculata