Topic 4
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Central dogma
DNA —transcription-> RNA —translation-> Protein (Dogs can’t race lazy people) Process: instructions in DNA converted into functional product
Where is DNA info stored?
In the nucleotide sequence
Genotype
DNA sequence of an organism
Phenotype is the result of?
Protein production aka gene expression
What is the link between genotype and phenotype?
Proteins
What is the intermediate between genes and the proteins for which they code?
RNA
Transcription
DNA-directed synthesis of RNA Produces messenger RNA
Translation
Synthesis of a polypeptide Occurs under directions of mRNA Occurs on ribosomes
Differences in gene expression between Prokaryotes and Eukaryotes -prokaryotes
-no nuclear envelope to separate transcription and and translation -mRNA produced by transcription is immediately translated (No RNA processing) -translation can start before end of transcription