cell properties
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scale of cells, tissues and organs in order
cells < tissues < organs
3 components of intestines
epithelial tissues, connective tissues, muscle tissues
how cells are held together (assembly of cells)
cell-cell adhesions and/or extracellular matrix
4 types cell junctions and their respective locations across the membrane
apical: tight junctions lateral: adherens junctions (in the belt), desmosomes and gap junctions basal: hemidesmosomes
cell junctions that form the junctional complex (3)
tight junctions, adherens junctions, desmosomes
cell-matrix anchoring junctions connect ___ to ___
basal surface of the cell to the basal lamina
tight junctions form a seal between ___ and a fence between ___
cells plasma membrane domains
anchoring junctions respond to ___ from ___
tension from inside and outside the tissue
channel forming junctions regulate ___ and ___ between cells gap junctions in particular provide ___
metabolic and electrical communication between cells a passageway linking cytoplasm of adjacent cells
function of signal-relaying junctions
allow communication between cells
transmembrane proteins link ___ to ___
cytoskeleton to extracellular structures or other cells
function of cadherins
linking a cell to neighbouring cells
function of integrins
linking a cell to the extracellular matrix
an adherens junction allows cells to ___ and ___ by forming ___ around the cells
respond to tension increase their filament crosslinking a belt
anchoring junctions: desmosomes provide ___
additional tensile strength to epithelial tissues
anchoring junctions: hemidesmosomes
anchor keratin filaments in the epithelial cell to the basal lamina
gap junctions provide ___ with a direct channel of ___
neighbouring cells inter-cytosolic communication
compound that has a similar function to gap junctions in plant cells, and state a difference
plasmodesmata, but they are larger channels
connexons are ___ they facilitate ___ between ___
fundamental structural and functional units of gap junctions direct communication and transport between the interiors of adjacent cells
cadherins and their 2 main classifications
family of adhesion molecules classical and non-classical
3 cellular adhesion molecules in the immunoglobulin superfamily
ICAMS - intercellular cell adhesion VCAMS - vascular cell adhesion NCAM - neural cell adhesion molecule
how integrins can become activated
binding to an extracellular matrix molecule or to intracellular adaptor proteins that link to the cytoskeleton
connective tissue
tissue that surrounds other tissues
basal lamina is a sepcialised form of ___, it can be found ___, ___ or ___
specialised form of ECM surrounding cells, underlying epithelia or lying between two cell sheets