Exam 2 vocab

site on the gene where transcription factors bind. TATA box located directly upstream of the start site. TATA box has consensus sequences

required to assemble the transcription complex TFII. mediator coordinates.

mediator coordinates.

elements which enhance transcription by helping transcription factors bind to promoter, activators bind to enhancers. can be up or down stream.

proteins which may alter chromatin structure or interact with the mediator or other transcription factors.

bind to upstream elements that are regulated by an inducer

proteins which may alter chromatin structure or interact with the mediator or other transcription factors.

areas rich in CG repeats. methylation of c can inhibit gene expression due to enhanced chromatin compaction by methyl binding proteins.

Bind to

made up of TATA binding proteins and TBP-associating factors. can bind to the TATA binding complex. binds to DNA and bends it through electrostatic properties.

bind to DNA at TFIID. which through electrostatic properties can bend open proteins.

bind to the rest of the preinitiation complex. phosphorylates the carboxyl terminal of RNA POL II

reads class I genes, rRNA

reads class II genes (genes encoding proteins). produces mRNA. reads 3 to 5

tRNA, small rRNA and small viral RNAs

a multiprotein complex which regulates transcription between activators, coactivators, transcription factors and TFIID. Coordinates between regulatory and basal TF, allowing basel to bind.

interact with repressor proteins which block activator/ coactivator from interacting with transcription factors or the initiation complex.

act as boundaries between genes to ensure the “correct” gene gets transcribed.

normal form of DNA sequence

organisms that contain one or more mutations.

noncoding DNA

coding DNA