Drugs of Abuse
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Is a psychostimulant and sympathomimetic drug
Methampethamine
3 Signs of Opiate Abuse
Pinpoint Pupils Nodding Withdrawal
Is a crystalline tropane alkaloid that is obtained from the leaves of the coca plant
Cocaine
Chemical name for Cocaine
Benzomethyl ecgonine
What are the 3 Opiate Receptor
µ , Y , ε - receptor
Use to treat the effects of cocaine
Tricyclic anti-depressant such imipramine
Drugs of Abuse 5 General Mechanism of Action
Opiates , Dopaminergic pathway stimulant , Tranquilizers , Barbiturates ; Sedative/Hypnotic , Hallucinogens
Coexist on inhibitory neurons causing release of GABA at the synapses reducing the dopaminergic effect
Diazepam ( Valium) and other Benzodiazepams
2 Major Tranquilizers appear to block attachment of dopamine to the dendritic receptors bloking the stimulatory effects of dopamine
Halopredol ( Haldol ) , Chlorpromazine
2 Opiates µ -receptor which produce a general analgesic state
Morphine and Heroin
Give 3 example of Drugs which is an Opiate
Morphine , Codeine and Heroine
Marijuana is a psychoactive drug extracted from the plant ______
Cannabis sativa sub. species indica
The herbal form of the drug are consist of _________ and __________
Dried mature flower and subtending leaves of pistillate Female plant
Major biologically active chemical compound in cannabis
Δ 9 - Tetrahydrocannabinol
2 intoxiciant form of Marijuana
Hashish and Hash oil
A concentrated resin composed of heated glandular trichomes that have been physically extracted, usually by rubbing , sifting or with ice.
Hashish
Hashish 2 other names
Pressed Kief or Charas
Marijuana is locally known as
Pot, Damo , Jutis, Mary jane and Hash
Smoking Devices used in marijuana
Screened Bowl , Bongs , Chillums , Paper-wrapped joints and wrapped blunts
The minimum amount of THC required to have a perceptible psychoactive effect is about _____ per kilogram of body weight
10 µg/kg of body of weight
Half life and complete elemination of Marijuana
1 week half life and complete elemination 1 month
How many percent of unchanged metabolites (THC) are excreted
Marijuana metabolites undergo ______
enterohepatic recirculation
True or False . About marijuana 1/3 is excreted in the bile and 2/3 is excreted in the urine
False