The CNS and neurotransmitters
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What is the CNS?
• Made up of the brain and spinal cord • Responsible for processing and transmitting information throughout the body
What are the main functions of the CNS?
The CNS controls sensory information, motor commands, and higher functions such as thinking, memory, and decision-making.
What are the main functions of the spinal cord?
• Carries messages between body and brain • Receives sensory info from skin, joints, muscles • Carries motor instructions controlling movement.
What does the brain do in the CNS?
• receives info from the senses • processes the info • controls thoughts, memory, emotions and planning. • send instructions back to the body.
What is a neuron?
Specialised nerve cell that; - Receives - Processes - and transmits info through electrical and chemical signals.
What is the structure of a neuron?
• Cell body: Contains the nucleus and processes information. • Dendrites: Receive electrical signals from other neurons, triggering an action potential within the cell. • Axon: Transmits electrical signals away from the cell body to other neurons or muscles (so to other axon terminals). • Axon terminals: Pass nerve impulses from cell body to the parts of the body they can’t control/activate. terminal boutons at end, bulb-shaped structures - vesticles - store nts for synaptic transmission.
What is the function of the myelin sheath?
• is a fatty insulating layer around the axon, • speeds up transmission of electrical impulses.
What is the role of a neuron?
• Neurons transmit electrical impulses throughout the body, allowing communication between the brain, spinal cord, and muscles/organs.
Three main types of neuron are
• Motor - transmits messages from CNS to muscles • Inter (relay) - connect neurons to other neurons • Sensory - carry info from senses to CNS
What is synaptic transmission?
the process by which neurotransmitters are released from the axon terminal of one neuron and cross the synapse to bind to receptors on the dendrites of another neuron, transmitting a signal.
What happens during synaptic transmission?
• An action potential travels down the axon to the axon terminal. • Neurotransmitters are released into the synapse. • These neurotransmitters bind to receptors on the next neuron’s dendrites. • The signal is either excited or inhibited, depending on the neurotransmitter and receptor type.
What is the role of dopamine?
Dopamine is a neurotransmitter involved in regulating mood, motivation, and reward. It plays a key role in pleasure and reward systems and is involved in conditions like Parkinson’s disease and schizophrenia.
What is the role of serotonin?
Serotonin is a neurotransmitter that regulates mood, appetite, sleep, and memory. It is linked to feelings of well-being and is often associated with depression and anxiety when levels are low. SSRIs increase serotonin levels.
What is glutamate?
Glutamate is the brain’s main: - excitatory neurotransmitter. It increases neural activity and is important for: - learning, - memory.
What is the difference between excitatory and inhibitory neurotransmitters?
Excitatory neurotransmitters: increase likelihood of neuron firing. Inhibitory neurotransmitters: decrease likelihood of neuron firing. Example: glutamate = excitatory GABA = inhibitory
Action potential
• The method the nerve impulse passes down the axon. • Tiny electrical impulse that’s triggered by change in the electrical ‘potential’ of the neuron. • ‘the electrical impulse travelling down the axon.’
What is the resting potential of a neuron?
At rest, a neuron has a charge of: -70mV This means the inside is more negative than the outside
What is depolarisation?
Depolarisation occurs when: - positively charged sodium ions enter the neuron, - making the inside more positive. If the neuron reaches: -55mV an action potential is triggered.
What is reuptake?
Reuptake is when unused neurotransmitters are: - reabsorbed into the presynaptic neuron. This helps “turn off” the signal.