Blood Transfusion!
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What does Blood tracking allow
Electronic tracking and vein to vein audits of blood components
Name for the system responsible for temperature monitoring
Connected automated monitoring previously known as tutela
Blood donation in the uk
• voluntary unpaid donors -restrictions on donors eg dates of previous donations/transfusions,pregnancy,cvd
Purpose of donor selection
-protect donor from harm -protect recipient from any ill effects of transfusion such as infectious disease
Donor criteria
-fit and healthy -between 50-158kg -aged between 17-66(70 if you have given blood before)
Clinical donor restrictions
-donate 470 ml of their blood which should be no more than 13% of their total circulating volume in order to prevent anaemia and vasovagal reactions eg fainting -frequency of donation(16 weeks) -no carryover effect on recipient eg aspiring or medical condition such as diabetes -minimum pre donation hub concentration is 125g/l for female and 135g/l for males -minimum hb should be 40 g
In the uk what are donations screened for
• HBV, HCV, HEV • HIV1 and HIV2 • HTLV 1 and HTLV 2 • Treponema palladium (Syphilis)
Optional testing in the uk
Malaria, West Nile Virus (according to travel /residence history) - Cytomegalovirus (CMV) - Trypanosoma cruzi (Chagas disease)
What is the variant creutzfeldt Jakob disease
-disease causing agent is a prion -humans eat infected meat=vCJD exposure=symptoms=decades -can be transmitted from person to person via medical products/instruments
Leucodepletion
-minimises transfusion associated gvHD9