specific little proteins and genes :(
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Cre recombinase
removes genetic sequences between two LoxP sites
LoxP
flanks gene of interest in knockout
macho mRNA
muscle specific transcription factor, necessary for muscle differentiation
Hox
axis formation
POU
pituitary development
Lim
head development
Pax
neural specification
bHLH
muscle and nerve specification
bZip
liver differentiation
Sry-Sox
mammalian primary sex determination
MADS-box
floral organ identity
Lin-14
transcription factor that controls stage-specific cell-fates in larval phase
Lin-4
miRNA that encodes 21-nucleotide RNA complementary to repeated sequence
catenins
anchor cadherins
E-cadherin
early mammalian embryonic cells
N-cadherin
CNS development
P-cadherin
placenta
R-cadherin
retina
fibronectin, laminin, collagen
ECM macromolecules
fibronectin
binds to cell surface receptors (integrins), mediates cell adhesion
integrins
ECM molecule receptors
activin
paracrine factor of TGF-B superfamily
heparan sulfate proteoglycans (HSPGs)
glycoprotein containing one or more covalently attached HS chain, binds to various paracrine factors
Oct4, Nanog, Sox2
maintain uncommitted stem-cell state and pluripotency