Laboratory Markers of Cardiac Damage and Function

A serum TnT concentration is of most value to the patient with an MI when a. The CK-MB has already peaked and returned to normal concentrations b. The onset of symptoms is within 3 to 6 hours of the sample being drawn c. The myoglobin concentration is extremely elevated d. The TnI concentration has returned to normal concentrations

A normal myoglobin concentration 8 hours after the onset of symptoms of a suspected MI will a. Essentially rule out an acute MI b. Provide a definitive diagnosis of acute MI c. Be interpreted with careful consideration of the TnT concentration d. Give the same information as a total CK-MB

Which of the following analytes has the highest specificity for cardiac injury? a. TnI b. CK-MB mass assays c. Total CK-MB d. AST

Which of the following newer markers of inflammation circulates in serum bound to LD and HDL? a. Lipoprotein-associated phospholipase A2 b. CK-MB c. cTnI d. hsCRP

A person with a confirmed blood pressure of 125/87 would be classified as a. Prehypertension b. Normal c. Stage 1 hypertension d. Stage 2 hypertension

Rheumatic heart disease is a result of infection with which of the following organisms? a. Group A streptococci b. Staphylococcus aureus c. Pseudomonas aeruginosa d. Chlamydia pneumoniae

Which of the following defects is the most common type of congenital CVD encountered? a. Ventricular septal defects (VSD) b. Tetralogy of Fallot c. Coarctation of the aorta d. Transposition of the great arteries

Which of the following cardiac markers is the most useful indicator of congestive heart failure? a. BNP b. TnI c. CK-MB d. Glycogen phosphorylase isoenzyme BB

Which of the following is the preferred biomarker for the assessment of myocardial necrosis? a. CK b. AST c. CK-MB d. TnI

Which of the following is NOT a feature of an ideal cardiac marker? a. Ability to predict future occurrence of cardiac disease b. Absolute specificity c. High sensitivity d. Close estimation of the magnitude of cardiac damage