Organic Mechanisms
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Haloalkane to alcohol
Mechanism: - Nucleophilic Substitution Reagents: - Aqueous potassium hydroxide Condition: - Heat under reflux
Haloalkane to nitrile
Mechanism: - Nucleophilic Substitution Reagent: - Ethanolic potassium cyanide Condition: - Heat under reflux
Haloalkane to amine
Mechanism: - Nucleophilic Substitution Reagent: - Ethanolic ammonia Condition: - Heat under pressure
Friedel Crafts Acylation
Mechanism: - Electrophilic Substitution Reagent: • AlCl₃ • Acyl Chloride Condition: - Reflux Change in functional group: - Benzene –> Phenyl ketone
Nitration of Benzene
Mechanism: - Electrophilic Substitution Reagent: • Concentrated HNO₃ • Concentrated H₂SO₄ Change in functional group: - Benzene –> Nitrobenzene
Reduction of Nitrobenzene
Mechanism: - Reduction Reagent: • Sn or Fe • HCl Condition: - Heat Change in functional group: - Nitrobenzene –> Phenylamine
Acyl Chloride reactions
Mechanism: - Nucleophilic Addition Elimination Reagent: • Water • Alcohol • Ammonia • Primary Amine Condition: - Room Temperature
Reagent for the formation of a carboxylic acid from an acyl chloride (1)
Water
Reagent for the formation of a ester from an acyl chloride (1)
Alcohol
Reagent for the formation of a primary amide from an acyl chloride (1)
Ammonia
Reagent for the formation of a secondary amide from an acyl chloride (1)
Primary Amine
Halogenoalkane –> alkene
Mechanism: - Elimination Reagent: - KOH (base) in ethanol Condition: - Heat
Synthesis of halogenoalkanes
Mechanism: - Free Radical Substitution Reagent: - Halogen Condition: - UV Light
Condition for Electrophilic Addition
• Room Temperature
Industrial Hydration
Mechanism: - Electrophilic Addition Reagent: - Concentrated H3PO4 Condition: - Heat temperature + pressure Change in functional group: - Alkene –> Alcohol
Dehydration of alcohols
Mechanism: Elimination Reagent: concentrated phosphoric acid Conditions: Heat under reflux Change in functional group: Alcohol –> Alkene
Reagents for oxidation of alcohols
Potassium Dichromate + dilute H2SO4
Condition for conversion of alcohol to aldehyde
Heat + Distillation
Condition for conversion of alcohol to carboxylic acid
Heat under reflux
Condition for conversion of alcohol to ketone
Heat under reflux
Reduction of carbonyls
Mechanism: Nucleophilic Addition Regaent: NaBH4 in aqueous ethanol Conditions: Room temperature and pressure Change in functional group: Aldehyde/Ketone –> Alcohol
Formation of hydroxynitriles
Mechanism: Nucleophilic Addition Reagents: NaCN and dilute H2SO4 Conditions: Room temperature and pressure Change in functional group: Aldehyde/Ketone –> hydroxynitrile
Formation of a quaternary ammonium salt:
Mechanism: Nucleophilic Substitution Reagents: Excess Halogenoalkane + Ethanolic Ammonia Conditions: Heat under pressure
Formation of a polyamide:
Mechanism: Condensation Polymerisation Reagents: Dicarboxylic acid + diamine OR Diacylchloride + diamine