Lecture 4: Hematology II

They contain a protein called, hemoglobin to transport oxygen and carbon dioxide from the lungs to tissue

6 to 8 µm

It defends the body against infection and disease by ingesting foreign materials and cellular debris by destroying infectious agents and cancer cells or by producing antibodies

6 to 22 µm

Thrombocytes are pieces of very large cells in the bone marrow called megakaryocytes. They help form blood clots to slower stop bleeding, and help wounds heal.

1.5 to 4 µm

Differential: counting and identifying 100 leukocytes. Evaluation of thrombocytes: estimation of platelet count per oil immersion field. Erythrocyte morphology: assesses size, and shape of RBCs.

Is a polychromatic stain consisting of a mixture of eosin and methylene blue.

Using differential counters

The RBCs must be barely touching, not overlapping. WBCs are not distorted or misshapen.

It is the irreversible condensation of chromatin in the nucleus of a cell undergoing necrosis or apoptosis

The remnants of leukocytes. They have no cytoplasm, and sometimes all that can be seen of smashed nuclei. Smudge cells are formed from leukocytes, typically lymphocytes, that are fragile, and are destroyed or smudged in the physical process of making a smear.

An increase number of platelets

A decreased number of platelets

It means the RBCs are very pale and showing an increased area of central power making up more than 1/3 out of the cell

It is the result of a decrease in the hemoglobin content of the cell and is often accompanied by a decrease in cell size

It is variation and staining color

It is a general term indicating increased variation in the size of RBCs in the blood film

It means that a patient does not have enough iron, which leads to decrease hemoglobin

It means that the body makes an abnormal form of hemoglobin

Variation in the size of an RBC

Variation in shape of an RBC