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Post-translational Modifications of Proteins
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Total cards: 7•Content version: v4•Public deck•Updated: 8/1/2026
Card preview (7)
#1
Front (Question)
Phosphorylation
Back (Answer)
• Add phosphate group on the side chain of AA. • May increase or decrease functional activity • serine, threonine or tyrosine
#2
Front (Question)
Hydroxylation
Back (Answer)
• A hydroxyl group (OH) • Can effect protein stability and protein-protein interaction
#3
Front (Question)
Methylation
Back (Answer)
Add methyl (CH3) group
#4
Front (Question)
Acetylation
Back (Answer)
• Add acetyl group • i.e. Histone (DNA structure) • increase/decrease transcription (methylation) regulates gene expression (acetylation)
#5
Front (Question)
Trimming
Back (Answer)
Trypsinogen into trypsin
#6
Front (Question)
Lipidation
Back (Answer)
• Add lipid • increasing their binding affinity to biological membranes (cell and organelle membranes)
#7
Front (Question)
Glycosylation
Back (Answer)
• Add glycan (carbohydrate, polysaccharide) • May effect cell-cell adhesion and communication