Chapter 17
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Leukemia
An increase in the number of leukocytes in the circulating blood
Phagocyte
A cell that can engulf or devour bacteria, foreign matter, or other cells
Leukopenia
A decrease in the number of leukocytes in the circulating blood
White blood cellS: functions
Engulfs foreign matter Produces antibodies
White blood cells: classifications
Granulocyte: presence of granules in cytes A) neutrophils: stain in neutral fashion B) basophils: stain basic C) eosinophils: stain acidic Agranulocyte:no granules in cyte Monocytes Lymphocyte
White blood cells: life span
Minutes to years
White blood cells: concentration
Thousands/microliter
Neutrophils
89% of total granulocytes Most important white blood cell for fighting acute infection Pass through capillary pores by diapedesis Exhibit ameboid motion in tissue Phagocytize foreign particles Average of 20-25 bacteria removed by each neutrophil
Eosinophils
10% of granulocytes Behaves similarly to neutrophils Numbers increase during allergic reactions Primarily detoxify foreign proteins Numbers increase with some parasites Lowered eosinophil counts have been associated with stress
Basophils
Approximately one percent or less of granulocytes Little or no phagocytic action Prevents intravascular blood coagulation Prevents blood and lymph stasis during inflammation Contains heparin (anticoagulant) Vasoconstrictor (histamine)
Monocytes
Originate in bone marrow Large size Superior phagocytic properties Predominant during chronic infection After moving to tissue...converted to macrophages
Lymphocytes
Formed in lymph nodes Can revert to monocytes, hemocytoblast, fibroblast Can form and secrete antibodies b form: produces antibodies T form: fights viral infections
Leukemia
Abnormal growth and development of white blood cells Leukemoid reaction: UNDER abundance of neutraphis WBC chronic lymphocytic leukemia: over abundance of neutraphis WBC
Leukopenia
Too few WBC
Platelets
Fragments produced from megakaryocytee Makes sure body has zero leakage Plugs hole when bruised Too many platelets causes clots Too few causes hemeridge