ANTI-MALARIALS

ANTI-MALARIALS Malaria is caused by ____ parasite

ANTI-MALARIALS Vector of malaria

ANTI-MALARIALS 40%, very chronic and reinfection of liver cells Plasmodium species

ANTI-MALARIALS 50%, Most common, severe, and infects 65% of the patient’s erythrocytes Plasmodium species

ANTI-MALARIALS 10%, relapses are common Plasmodium species

ANTI-MALARIALS Least common Plasmodium species

ANTI-MALARIALS Zoonotic Plasmodium species

CINCHONA ALKALOIDS Lethal for all Plasmodium schizonts and gametocytes

CINCHONA ALKALOIDS Quinidine is primarily indicated for ____.

CINCHONA ALKALOIDS More potent and toxic anti-malarial that is a stereoisomer of quinine

CINCHONA ALKALOIDS For nocturnal leg cramps

CINCHONA ALKALOIDS Adverse effect of Quinine Sulfate

CINCHONA ALKALOIDS For malaria caused by chloroquine-resistant P. falciparum strains

CINCHONA ALKALOIDS Toxic syndrome characterized by tinnitus, headache, nausea, and disturbed vision.

4-AMINOQUINOLINES Main antimalarial drug used for both prophylaxis and treatment of malaria

4-AMINOQUINOLINES Highly protein bound anti-malarial

4-AMINOQUINOLINES Prophylaxis for malaria that is associated with higher incidence of hepatitis and agaranulocytosis

4-AMINOQUINOLINES Drug of choice for malarial suppression

4-AMINOQUINOLINES Drug of choice for Erythrocytic falciparum malaria except resistant strains

8-AMINOQUINOLINES MOA of primaquine

8-AMINOQUINOLINES Drug of choice for acute attack of Plasmodium vivax that has the narrowest spectrum of activity

4-AMINOQUINOLINES A schizonticide that exacerbate mental disorders

8-AMINOQUINOLINES Most effective against malarial parasite in the liver, but not effective against parasites within erythrocytes

POLYCYCLIC Tetracycline that inhibits the pathogen’s protein synthesis