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A1.2 HL Hershey and Chase (1952)

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Total cards: 7•Content version: v4•Public deck•Updated: 8/1/2026

Card preview (7)

#1
Front (Question)

What question did Hershey and Chase test?

Back (Answer)

Is genetic material DNA or protein?

#2
Front (Question)

What organism did they use?

Back (Answer)

T2 bacteriophage (virus infecting E. coli).

#3
Front (Question)

How did they label DNA?

Back (Answer)

Radioactive ³²P (DNA contains phosphorus).

#4
Front (Question)

How did they label protein?

Back (Answer)

Radioactive ³⁵S (proteins contain sulfur in amino acids).

#5
Front (Question)

What was the experiment procedure?

Back (Answer)

• Phages infect bacteria. • Blender shakes off viral coats. • Centrifuge separates bacteria (pellet) from viral coats (supernatant).

#6
Front (Question)

What were the results?

Back (Answer)

³²P (DNA) found in bacteria. ³⁵S (protein) remained outside.

#7
Front (Question)

What did they conclude?

Back (Answer)

DNA is the genetic material, not protein.