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NPNs: Uric Acid

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Total cards: 24•Content version: v4•Public deck•Updated: 8/1/2026

Card preview (24)

#1
Front (Question)

Major Product of Purine Catabolism

Back (Answer)

Uric acid

#2
Front (Question)

Purine is made from

Back (Answer)

Guanine + Adenine (PURGA)

#3
Front (Question)

Pyrimidine

Back (Answer)

pCUT Pyrimidine = Cytosine, Uridyl, Thymine

#4
Front (Question)

Formed from xanthine oxidase from liver and intestine

Back (Answer)

Uric acid

#5
Front (Question)

Uric acid exist as _________ urates in plasma

Back (Answer)

Monosodium urates

#6
Front (Question)

> 6.8 g of urate crystals may form

Back (Answer)

Precipitate in tissues (gout arthritis)

#7
Front (Question)

Organic Meat Legumes Plant

Back (Answer)

High Purine Food

#8
Front (Question)

Confirms and Monitor Gout

Back (Answer)

Uric acid

#9
Front (Question)

diagnosis of Renal Calculi using Uric Acid uses what specimen

Back (Answer)

Urine

#10
Front (Question)

Uric acid can be used to monitor Uric Acid Nephropathy in cancer patient that undergoes chemotherapy

Back (Answer)

Yes

#11
Front (Question)

Uric Acid Crystals: Reference Value Male Female

Back (Answer)

Male 3.5-7.2 mg/dL Female 2.6-6.0 mg/dL Urine 250-750 mg/day

#12
Front (Question)

Gout Increased Nuclear Metabolism Chronic Renal Disease Lesch Nyhan Syndrome

Back (Answer)

Hyperuricemia

#13
Front (Question)

• Occurs in male between 3rd and 5th decade of life • Negative birefringence crystals in synovial fluid • acute inflammatory arthritis • can lead to nephrothiliasis

Back (Answer)

Gout

#14
Front (Question)

Seen in leukemia, Lymphoma, MM and PV, Hemolytic and Megaloblastic Anemia Treatment: Allupurinol

Back (Answer)

Increased Nuclear Metabolism

#15
Front (Question)

Decreased GFR and tubular secretion BUA >10 mg/dL

Back (Answer)

Chronic Renal Disease

#16
Front (Question)

Inborn Error of Purine Metabolism

Back (Answer)

Lesh-Nyhan Syndrome

#17
Front (Question)

Orange sand diaper syndrome ; deficiency of HGPT (Hypoxanthine Guanin Phosphoribosyl Transferase

Back (Answer)

Lesh-Nyhan Syndrome

#18
Front (Question)

Seen in patient with Preeclampsia

Back (Answer)

Inc. BP Inc. Protenuria Inc. Uric Acid

#19
Front (Question)

Treatment for Hyperuricemia: Inhibits xanthine oxidase activity ; lowering UA in serum without affecting excretion in kidney

Back (Answer)

Allopurinol

#20
Front (Question)

Treatment for Hyperuricemia: Drugs that lower the serum UA but increase excretion of UA in urine = Prone to uric acid stones if not maintained at Alk pH.

Back (Answer)

Uricosuric drugs (Probenecid and Sulfinpyrazone)

#21
Front (Question)

Treatment for Hyperuricemia: • Neither excretion nor production is affected • Alters phagocytic effect of leukocytes in uric acid crystals in tissues • used in symptomatic patients

Back (Answer)

Colchicine

#22
Front (Question)

• Fanconi Syndrome • Wilson’s disease • Hodgkin’s disease • Overtreatment of Allopurinol • Chemotherapy with azathioprine / 6-mercaptopurine • Liver Disease

Back (Answer)

Hypouricemia

#23
Front (Question)

Laboratory Methods for Uric Acid: Chemical Method that uses Principle: Redox Reaction

Back (Answer)

Caraway Method / Phosphotungstic Acid Method

#24
Front (Question)

Laboratory Methods for Uric Acid: Product produced in Caraway Method / Phosphotungstic Acid Method

Back (Answer)

Tungsten BLUE + ALLANTOIN + CO2