Affects of Mutations
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what is a mutation?
• change to the base sequence of DNA
what could be the affects of a mutation?
• no change to amino acid sequence • change to a single amino acid sequence • change to sequence of many amino acids
what happens when there is no change to amino acid sequence?
• amino acids are coded for by more than one triplet a DNA • DNA is degenerate
what happens when there is a single change to amino acid sequence?
• changes one DNA triplet • changes the translation of one amino acid • change the primary (1*) structure of the polypeptide • change the hydrogen/iconic bonding • change the tertiary (3*) of the protein
what happens when there are many changes to amino acid sequence?
• frame shift changes to sequence of all the following DNA triplets • changes all the flowing amino acids in sequence • changes to the primary structure • changes the hydrogen/iconic bonding • changes 3* structure • can be caused by insertion or deletion