Week 3
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Define observational studies
A study that is done where a particular trend or concept is observved
Define experimental studies
Experimental studies are ones where researchers introduce an intervention and study the effects.
3 types of research
Descriptive Relational Causal
Hierarchy of evidence (1 - 7)
• Background info (Lowest, weakest, worst) • Case - controlled studies / Reports • Cohort studies • Randomised controlled trials (RCTs) • Critically - appraised individual articles • Critically - appraised topics • Systematic reviews
Define cross - sectional study
collect data from many different individuals at a single point in time
Advantages and disadvantages of cross - sectional studies
Advantages - More time - efficent - Often less expensive - Reduced likelihood of attrition Disadvantages - Less powerful (within group variance is higher) - 'Cohort problem". E.g. assessing physical activity participation but neglecting to recognise that school PE changes over the years
Define case-control study
A study that compares two groups of people: those with the disease or condition under study (cases) and a very similar group of people who do not have the disease or condition
Define cohort study
A study design where one or more samples (called cohorts) are observed over a period of time. The incidence of disease in the exposed group is compared with the incidence of disease in the unexposed group.
Cohort study advantages and disadvantages
Advantages - Potentially very rich data set - Same people are measured, so minimises the effect of other variables Disadvantages - Drop out, mortality - Non - equivalence of those who dropped out and those who remained in the study. E.g. may no longer representative of the target population - Familiarity with the experiment. E.g. responses over time may be influenced by previous tests
What are the 4 types of observation studies
Cohort case studies cross-sectional case-control
What are the 3 experimental study types
Single group interventions Quasi - experimental Randomised controlled trials
Define single group interventions
• Take a group of people, intervene Measurements at baseline and follow - up (s)
Define quasi - experimental study
• Measures are completed in an intervention and comparison group with similar characteristics • Group are not randomised
Quasi - experimental advantages and disadvantages
Advantages - Useful when randomisation is difficult - Can save time and resources - Maybe a reasonable alternative to RCT Disadvantages - Groups may differ, introducing bias - Need to document characteristics - Need to acknowledge potential bias - Weakens potentional casual effects
Define randomised controlled trials
• Controlled • Random allocation to groups Pre and post measures
Define systematic review
A systematic review is a review of a clearly formulated question that uses systematic and reproducible methods to identify, select and critically appraise all relevant research
Why do a systematic review
• Present the evidence base in an accessible format. Helping readers find the results of research quickly and to assess the validity, applicability and implications of those results • Provide more reliable findings from which conclusions can be drawn and decisions made • The needs of healthcare providers, consumers, researchers, and policy makers