Chapter 5
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Are natural chemicals generally safer than synthetic chemicals ?
Not able to predict toxicity based on it being natural or synthetic
What makes a substance toxic ?
Degree in which a substance can cause damage to an organism
How is toxicity measured in a practical sense ?
The lower the ld50 the more toxic
Toxicant
Potential harm
Hazard
Level of exposure from toxin that results in harm
Ld50
Dose of which substance is lethal to 50 percent of the population
NOEL
No observed effect level
ADI
Acceptable dietary intake
EDI
Estimated daily intake
What factors should be considered to determine if a toxic posses a hazard to the general population
Ld50
Who determines standard values for adi and sets regulations for potential toxicants in food ?
Who , FDA, CDC
Acute exposure
Rapid