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CREATINE KINASE

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Total cards: 24•Content version: v4•Public deck•Updated: 8/1/2026

Card preview (24)

#1
Front (Question)

What is the reaction of CK?

Back (Answer)

Creatine + ATP <> Phosphocreatine + ADP

#2
Front (Question)

What is the major phosphorylated compound in muscle?

Back (Answer)

Phosphocreatine

#3
Front (Question)

When muscles contracts, what happen?

Back (Answer)

ATP is consumed to form ADP. CK catalyzes the resphosphorylation of ADP to for ATP

#4
Front (Question)

In terms of tissue course of CK, enumerate where it it GREATEST and SMALLER QUANTITIES.

Back (Answer)

GREATEST: Striated muscle and Heart tissue SMALLER QUANTITIES: Bladder, Placenta, GIT, Thyroid, Uterus, KIdney, Lung, Prostate, Spleen and Pancreas

#5
Front (Question)

How much protein CK activity is present is striated muscle and Heart tissue?

Back (Answer)

Striated muscle : 2,500 Heart tissue: 500

#6
Front (Question)

Which is devoid of CK activity?

Back (Answer)

Liver and RBC

#7
Front (Question)

What is the structure of CK?

Back (Answer)

A DIMER with 2 subunits

#8
Front (Question)

What is the MW of each subunit?

Back (Answer)

40, 000 Dalton’s

#9
Front (Question)

What are the 3 important Isoenzymes of the CK?

Back (Answer)

CK-BB (CK1) CK-MB (CK2) CK-MM (CK3)

#10
Front (Question)

The 3 important isoenzymes are mainly found in what part?

Back (Answer)

The cytosol

#11
Front (Question)

What are the forms of CK?

Back (Answer)

Type 1 and Oligomeric Mitochondrial CK.

#12
Front (Question)

What type of macromolecular form of CK has the Isoenzymes of CK forms complex with the Immunoglobulin?

Back (Answer)

Type 1

#13
Front (Question)

What type of Macromolecular form of CK is commonly found in adults with malignancy or liver conditions?

Back (Answer)

Oligomeric Mitochondrial conditions

#14
Front (Question)

CK1, CK2 and CK3 can be found in?

Back (Answer)

CK1 - Brain - Prostate - GUt - Lung - Bladder - Uterus - Placenta - Thyroid CK2 - Heart muscles CK3 - Skeletal (predominates) - Cardiac muscle

#15
Front (Question)

What do you call the 4th ISoenzyme?

Back (Answer)

CK-Mt (MItochodrial Isoenzyme)

#16
Front (Question)

To which does CK-Mt differ?

Back (Answer)

Immunologically and in electrophoretic mobility

#17
Front (Question)

CK-Mt constitutes up to ________ CK activity in the heart.

Back (Answer)

15%

#18
Front (Question)

This diagnostic significance of CK refers to a viral infection caused by entero virus and etc.

Back (Answer)

Viral myositis

#19
Front (Question)

This disease talks about an autoimmune disorder that happens in the muscle?

Back (Answer)

Polymyositis

#20
Front (Question)

Muscular dystrophy Duchenne type increases up to?

Back (Answer)

50x ULN

#21
Front (Question)

In this disease, the problem is the nerves.

Back (Answer)

Neurogenic muscle disease

#22
Front (Question)

What are the examples of Neurogenic Muscle Disease?

Back (Answer)

Myasthenia gravis Multiple sclerosis Poliomyelitis Parkinsonism Rhabdomyolisis

#23
Front (Question)

This NMD produce antibodies against nerves that control our muscles.

Back (Answer)

Myasthenia gravis

#24
Front (Question)

This disorder has the brain and the spinal cord conditions

Back (Answer)

Multiple sclerosis