Inhibitors

Competitive inhibitors bind at the active site preventing the substrate from binding Competitive inhibition can be reversed by increasing substrate concentration

Non competitive inhibitors bind away from the active site but change the shape of the active site preventing the substrate from binding Non competitive inhibition cannot be reversed by increasing substrate concentration

Feedback inhibition occurs when an end product in the metabolic pathway reaches a critical concentration. The end product inhibits an earlier enzyme blocking the pathway and so prevents further synthesis of the end product