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3.3.13.5 Action of Anticancer Drugs
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Total cards: 5•Content version: v4•Public deck•Updated: 8/1/2026
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#1
Front (Question)
What is an example of an anticancer drug?
Back (Answer)
Cisplatin
#2
Front (Question)
How does cisplatin affect the DNA helix?
Back (Answer)
The two chlorine atoms are replaced by guanine bases This distorts the shape of the cancer DNA As DNA is responsible for replication, this stops reproduction
#3
Front (Question)
How does cisplatin bond to guanine?
Back (Answer)
Nitrogen atoms of guanine have lone pairs which form dative covalent bonds with platinum
#4
Front (Question)
What kind of reaction is the bonding between cisplatin and DNA?
Back (Answer)
A ligand substitution reaction because the chloride ions are replaced by the guanine, due to being better ligands
#5
Front (Question)
What is the structure of cisplatin?
Back (Answer)
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