Lesson 1- Introduction
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What fields/disciplines are under bioinformatics
• Computer Science • Computational Biology • Mathematics • Statistics • Biology • Biochemistry • Chemistry
What are the goals of Bioinformatics
• Data management and storage • Sequence analysis • Structural Biology • Genome Annotation • Phylogenetics and Evolution • Functional genomics • Drug Discovery and Design • Personalized medicine • metagenomics • Systems biology
what goal of bioinformatics which aims to develop efficient ways to store, organize, and manage these large datasets
Data management and storage
what goal of bioinformatics is analyzing biological sequences, such as DNA, RNA, and protein sequences
Sequence analysis
what goal of bioinformatics which predict the three-dimensional structures of proteins and other biomolecules
Structural Biology
what goal of bioinformatics which used to annotate genomes, which involves identifying genes, regulatory elements, and functional elements within DNA sequences
Genome application
what goal of bioinformatics which helps in reconstructing the evolutionary relationships among species based on genetic data
Phylogenetics and Evolution
what goal of bioinformatics which used to study the functions of genes and proteins on a large scale (identifying gene functions, pathways, and interactions)
Functional genomics
what goal of bioinformatics that analyzes biological data to identify potential drug targets, predict the effects of candidate drugs, and optimize their properties for therapeutic purposes
Drug Discovery and Design
what goal of bioinformatics is analyzing individual patients’ genetic information to predict disease susceptibility, drug responses, and potential treatment strategies
Personalized Medicine
What field of bioinformatics involves studying genetic material directly obtained from environmental samples.
Metagenomics
What goal of bioinformatics aids in the integration of biological data from various sources to create comprehensive models of biological systems.
Systems Biology
Scope of application in Bioinformatics
• Structure analysis • Sequence analysis • Function analysis
information molecules of all living organisms
Nucleic Acids
The repeating subunits that creates the nucleic acids
Nucleotides
2 types of Nucleic acids
Deoxyribonucleic acid (DNA) Ribonucleic acid (RNA)
a unit of only the base and sugar without phosphates
Nucleoside
3 components of Nucleotides
• Nitrogeneous base • Phosphate group • Five-carbon sugar
types of nitrogenous bases
a. Pyramidines b. Purines
6-membere ring made up of carbon and nitrogen atoms
Pyramidines
Types of pyramidines
• C, T, U
a 6-membered ring fused to a 5-membered ring
Purines
types of purines
• A,G
Link covalently to nitrogenous bases
Five-carbon sugar (pentose)