Electrolytes
No description yet. This curated deck is ready for daily study.
Card preview (24)
Equal no. of cations and anions
Electroneutrality
Balance of charges
Electroneutrality
Average water content of the human body
40-75%
1/3 of total body water
ECF
2/3 of total body water
ICF
Normal plasma [?] water(Plasma: [?] > Whole blood) [?] solutes: (Increased in dehydration)
93%; 13% 7%
7% solutes:
-Proteins -Glucose -NPN -Lipids -Ions
Excretion of 10-20L H2O everyday
Vasopressin deficiency
Volume and Osmotic regulation
Sodium Potassium Chloride
Electrolytes EC = IC =
Na+ > Cl- > HCO3- > Ca2+(5th) > iPO4 K+ > Mg2+(4th)
Myocardial rhythm and contractility
Potassium
Neuromuscular excitability
Calcium Magnesium
Cofactors (enzyme)
Calcium Magnesium (CK) Zinc Chloride (AMS) Potassium
ATPase ion pump
Magnesium
Production and use of ATP from glucose
Magnesium Phosphate
Production and use of ATP from glucose
Magnesium Phosphate
Acid-base balance
Bicarbonate
Replication of DNA and translation of mRNA
Magnesium
Major contributor of osmolality (92%, together w/ Chloride and Bicarbonate)
Sodium
↑100 mg/dL glucose =
↓1.6 mmol/L sodium
Aldosterone Sodium Potassium = Magnesium
↑ Sodium ↓ Potassium = ↓ Magnesium
Atrial natriuretic factor Sodium
↓ Sodium
Excess water loss
Hypernatremia
Decreased water intake
Hypernatremia