Foundations in Immunology
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The bodies first line of defence is provided by what type of immune system?
Innate
Give roles of the innate immune system
Physical barriers (tight junctions between epithelia and mucous membranes) Phagocytic cells (macrophages and neutrophils) Soluble factors
State 3 primary lymphoid organs
Bone marrow Foetal liver Thymus gland (in these organs, lymphocytes are generated)
State 2 secondary lymphoid organs
Lymph nodes Spleen (these are where immune responses are initiated and lymphocytes are maintained)
What do mature immune cells do in secondary lymphoid tissues?
They interact with pathogens and initiate a response
State the fundamental properties of adaptive immune response.
Memory Specificity Recruitment of other defence mechanisms Diversity
Descibe the role of B lymphocytes in immunity. (4)
B cells differentiate into plasma. These cells synthesise antibodies specifically designed for use against the detected pathogen. The pathogen is recognised first by membrane bound antibody. The antibodies produced by plasma cells are soluble in plasma